cataracts genetic

Overview – Childhood cataracts

Cataracts occur when changes in the lens of the eye cause it to become less transparent (clear). This results in cloudy or misty vision.

The lens is the transparent structure located just behind the pupil (the black circle in the centre of the eye).

It allows light to pass through to the light-sensitive layer of tissue at the back of the eye (retina).

Cataracts most commonly affect older adults (age-related cataracts), but some babies are born with cataracts.

Children can also develop them at a young age. These are known as childhood cataracts.

Childhood cataracts are often referred to as:

  • congenital cataracts – cataracts present when a baby is born or shortly afterwards
  • developmental, infantile or juvenile cataracts – cataracts diagnosed in older babies or children

Cataracts in babies and children are rare. It’s estimated they affect between 3 and 4 in every 10,000 children in the UK.

Symptoms of cataracts in children

In children, cataracts can affect 1 or both eyes.

Cloudy patches in the lens can sometimes get bigger and more can develop, resulting in the child’s vision becoming increasingly affected.

As well as poor vision, cataracts can also cause “wobbling eyes” and a squint, where the eyes point in different directions.

When your child is very young, it can be difficult to spot signs of cataracts.

But your baby’s eyes will be routinely examined within 72 hours of birth and again when they’re 6 to 8 weeks old.

Sometimes cataracts can develop in children after these screening tests.

It’s particularly important to spot cataracts in children quickly because early treatment can reduce the risk of long-term vision problems.

You should visit your GP or tell your health visitor if you have any concerns about your child’s eyesight.

What causes cataracts in children?

There are a number of reasons why a child may be born with cataracts or develop them while they’re still young.

But in many cases it isn’t possible to determine the exact cause.

Possible causes include:

  • a genetic fault inherited from the child’s parents that caused the lens to develop abnormally
  • certain genetic conditions, including Down’s syndrome
  • certain infections picked up by the mother during pregnancy, including rubella and chickenpox
  • an injury to the eye after birth

How childhood cataracts are treated

Cataracts in children are often not too bad and have little or no effect on their vision.

But if cataracts are affecting your child’s vision, they can slow down or stop their normal sight development.

In these cases, surgery to remove the affected lens (or lenses) will usually be recommended as soon as possible.

Replacing the focusing power of the lens is as important as the surgery to remove it.

The affected lens may sometimes be replaced with an artificial lens during surgery, although it’s more common for the child to wear contact lenses or glasses after surgery to compensate for the lens that was removed.

It can be difficult to predict exactly how much better your child’s vision will be after treatment, although it’s likely there will always be a degree of reduced vision in the affected eye (or eyes).

But many children with childhood cataracts are able to live a full and normal life.

What are the risks?

Cataracts that affect vision that aren’t quickly treated can sometimes cause irreversible damage to eyesight, including a permanently lazy eye and even blindness in severe cases.

Cataract surgery is generally successful, with a low risk of serious complications.

The most common risk associated with cataract surgery is a condition that can affect artificial lens implants called posterior capsule opacification (PCO), which causes cloudy vision to return.

Another important risk of surgery is glaucoma, where pressure builds inside the eye.

Without successful treatment, glaucoma can cause irreversible damage to key structures in the eye.

Although some of the possible complications of cataract surgery can affect your child’s vision, they can often be treated with medication or further surgery.

Can cataracts in children be prevented?

It’s not usually possible to prevent cataracts, particularly those that are inherited (run in the family).

But following the advice of your midwife or GP to avoid infections during pregnancy (including making sure all your vaccinations are up-to-date before getting pregnant) may reduce the chances of your child being born with cataracts.

If you previously had a baby with childhood cataracts and are planning another pregnancy, you may wish to speak with your GP about whether genetic counselling would be appropriate.

Genetic counselling can help couples who may be at risk of passing an inherited condition on to their child.

Information about your child

If your child has had cataracts, your clinical team will pass information about him or her on to the National Congenital Anomaly and Rare Diseases Registration Service (NCARDRS).

This helps scientists look for better ways to prevent and treat this condition. You can opt out of the register at any time.

Page last reviewed: 25 October 2018
Next review due: 25 October 2021

Find out about childhood cataracts which occur when changes in the lens of the eye cause it to become less transparent, resulting in blurred or misty vision.

Studies of Families With Hereditary Cataracts

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
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The objective of this study is to discover the genes responsible for the development of hereditary cataracts in families. A cataract is clouding of the lens of the eye that obstructs the passage of light and may impair vision. Information from this study may provide a better understanding of why hereditary cataracts form and perhaps lead to the development of a test that can predict who will likely be affected and to what degree.

Patients or family members of patients with inherited cataracts who participate in this study will be asked questions about their family history, especially concerning eye disease or cataracts, and a family tree will be drawn. They will undergo a complete eye examination, including photographs to document the clarity or opacity of the lens. In addition, a small blood sample will be drawn for use in gene mapping studies of inherited cataract.

Studies of Families With Hereditary Cataracts The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it